Antiepileptic Intermediates Pregabalin Neuropathic-pain medicine

/ October 31, 2018

Model NO.: cas 148553-50-8
Molecular formula: C8H15NO2
Molecular weight: 157.21
EINECS No: 214-818-2
Trademark: zzyc
Transport Package: 25KG / cardboard bucket
Specification: Pregabalin
Origin: China
Model NO.: cas 148553-50-8
Molecular formula: C8H15NO2
Molecular weight: 157.21
EINECS No: 214-818-2
Trademark: zzyc
Transport Package: 25KG / cardboard bucket
Specification: Pregabalin
Origin: China
Antiepileptic Intermediates Pregabalin Neuropathic-pain medicine

Pregabalin
English Synonyms: 3 (S) - (AMINOMETHYL) -5-METHYLHEXANOIC ACID; (3S) -3- (AMINOMETHYL) -5-METHYLHEXANOIC ACID; PREGABALIN; Pregablin; 3- (Aminomethyl) -5-methyl-hexanoic acid; PREDNISOLONESODIUMPHOSPHATE ; (R) -Pregabalin; (S) -Pregabalin
CAS number: 148553-50-8
Molecular formula: C8H17NO2
Molecular weight: 159.23
EINECS number: 200-659-6
M.p. 194-196 ° C
Specific rotation D23 + 10.52 ° (c = 1.06 in water)
Flash point 9 ºC
Level: Medical grade
Content: 99%
Appearance: white powder
Uses: antiepileptic drugs and neuropathic pain medicine
Pregabalin belongs to a group of medicines known as anti-epileptic medicines, although it is prescribed for the treatment of several different conditions. You may have been prescribed it for the treatment of partial seizures, which is a type of epilepsy. A seizure is a short episode of symptoms which is caused by a burst of abnormal electrical activity in the brain. With a partial seizure, the burst of electrical activity stays in one part of the brain. Therefore, you tend to have localised or 'focal' symptoms. Pregabalin works by reducing the abnormal electrical activity in the brain. It is taken alongside other medicines for epilepsy.
Pregabalin is also prescribed to treat certain types of long-lasting pain caused by damage to nerves. 

COA:
 
ITEMS STANDARDS RESULTS
Appearance A white to off white powder White powder
    Identification A. Meets the requirement Complies
B. IR: similar to Reference Substance Complies
Loss on drying ≤0.5% 0.21%
Specific Rotation +10.0°~+13.0° +10.8°
Related Substances Any single impurity ≤0.1%
Total impurity ≤0.8%		 0.05%
0.10%
Purity By HPLC R-isomer ≤0.15% 0.10
Residue on ignition ≤0.1% 0.05%
Residual solvents Isopropyl alcohol ≤5000ppm
Ethyl Acetate   ≤5000ppm		 150ppm
250ppm
Heavy metals ≤10ppm Complies
Chlorides ≤0.05% Complies
Assay 98%~102.0% 99.8%
Conclusion Analyse according to Factory Standard , Conform


Application:

1. Pharmacological efficacy: Pregabalin is a novel γ-aminobutyric acid (GABA) receptor agonist, can block the voltage-dependent calcium channels to reduce neurotransmitter release.
2. Pregabalin,the main clinical for the treatment of peripheral neuropathic pain as well as part of adjuvant treatment of focal seizures.
3. Treatment of epilepsy in developing the most promising drug in a drug treatment better and more convenient administration. Pregabalin can also be used to treat pain and anxiety.


Usage:

LYRICA (pregabalin) oral solution, 20 mg/mL, is administered orally and is supplied as a clear, colorless solution contained in a 16 fluid ounce white HDPE bottle with a polyethylene-lined closure. The oral solution contains 20 mg/mL of pregabalin, along with methylparaben, propylparaben, monobasic sodium phosphate anhydrous, dibasic sodium phosphate anhydrous, sucralose, artificial strawberry #11545 and purified water as inactive ingredients.

Antiepileptic Intermediates Pregabalin Neuropathic-pain medicine


Q1: How to confirm the Product Quality before placing orders?
A: By sending you our available samples.
Or if you have special requirement on the goods, we can prepare samples according to your requirement for your confirmation.
 
Q2: Can you supply free samples?
A: Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can either pay the shipping cost or arrange a courier to collect the samples.
 
Q3: What's the MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10g.
For other low value product, our MOQ starts from 100g and 1kg.
 
Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price. 
 
Q5: How to place order and make payment?
A: You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by TradeManager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
 
 
Q6: How do you treat quality complaint?
 
A: All our products are strictly tested by our QC, and confirmed by QA; unqualified material will not be released to customer. 









  Antiepileptic Intermediates Pregabalin Neuropathic-pain medicine

Pregabalin
English Synonyms: 3 (S) - (AMINOMETHYL) -5-METHYLHEXANOIC ACID; (3S) -3- (AMINOMETHYL) -5-METHYLHEXANOIC ACID; PREGABALIN; Pregablin; 3- (Aminomethyl) -5-methyl-hexanoic acid; PREDNISOLONESODIUMPHOSPHATE ; (R) -Pregabalin; (S) -Pregabalin
CAS number: 148553-50-8
Molecular formula: C8H17NO2
Molecular weight: 159.23
EINECS number: 200-659-6
M.p. 194-196 ° C
Specific rotation D23 + 10.52 ° (c = 1.06 in water)
Flash point 9 ºC
Level: Medical grade
Content: 99%
Appearance: white powder
Uses: antiepileptic drugs and neuropathic pain medicine
Pregabalin belongs to a group of medicines known as anti-epileptic medicines, although it is prescribed for the treatment of several different conditions. You may have been prescribed it for the treatment of partial seizures, which is a type of epilepsy. A seizure is a short episode of symptoms which is caused by a burst of abnormal electrical activity in the brain. With a partial seizure, the burst of electrical activity stays in one part of the brain. Therefore, you tend to have localised or 'focal' symptoms. Pregabalin works by reducing the abnormal electrical activity in the brain. It is taken alongside other medicines for epilepsy.
Pregabalin is also prescribed to treat certain types of long-lasting pain caused by damage to nerves. 

COA:
 
ITEMS STANDARDS RESULTS
Appearance A white to off white powder White powder
    Identification A. Meets the requirement Complies
B. IR: similar to Reference Substance Complies
Loss on drying ≤0.5% 0.21%
Specific Rotation +10.0°~+13.0° +10.8°
Related Substances Any single impurity ≤0.1%
Total impurity ≤0.8%		 0.05%
0.10%
Purity By HPLC R-isomer ≤0.15% 0.10
Residue on ignition ≤0.1% 0.05%
Residual solvents Isopropyl alcohol ≤5000ppm
Ethyl Acetate   ≤5000ppm		 150ppm
250ppm
Heavy metals ≤10ppm Complies
Chlorides ≤0.05% Complies
Assay 98%~102.0% 99.8%
Conclusion Analyse according to Factory Standard , Conform


Application:

1. Pharmacological efficacy: Pregabalin is a novel γ-aminobutyric acid (GABA) receptor agonist, can block the voltage-dependent calcium channels to reduce neurotransmitter release.
2. Pregabalin,the main clinical for the treatment of peripheral neuropathic pain as well as part of adjuvant treatment of focal seizures.
3. Treatment of epilepsy in developing the most promising drug in a drug treatment better and more convenient administration. Pregabalin can also be used to treat pain and anxiety.


Usage:

LYRICA (pregabalin) oral solution, 20 mg/mL, is administered orally and is supplied as a clear, colorless solution contained in a 16 fluid ounce white HDPE bottle with a polyethylene-lined closure. The oral solution contains 20 mg/mL of pregabalin, along with methylparaben, propylparaben, monobasic sodium phosphate anhydrous, dibasic sodium phosphate anhydrous, sucralose, artificial strawberry #11545 and purified water as inactive ingredients.

Antiepileptic Intermediates Pregabalin Neuropathic-pain medicine


Q1: How to confirm the Product Quality before placing orders?
A: By sending you our available samples.
Or if you have special requirement on the goods, we can prepare samples according to your requirement for your confirmation.
 
Q2: Can you supply free samples?
A: Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can either pay the shipping cost or arrange a courier to collect the samples.
 
Q3: What's the MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10g.
For other low value product, our MOQ starts from 100g and 1kg.
 
Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price. 
 
Q5: How to place order and make payment?
A: You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by TradeManager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
 
 
Q6: How do you treat quality complaint?
 
A: All our products are strictly tested by our QC, and confirmed by QA; unqualified material will not be released to customer. 









 

We supply antibiotics for animals, shch as cattle hourse,sheep,pig, dog, cat and rabbit. The antibacterial drugs could inhibit or kill bacteria and used for the prevention and treatment of bacterial infections,such as e Campylobacter, E. coli, Haemophilus, Mycoplasma, Pasteurella and Salmonella spp. Its mainly including injection.powder.tablet.solution,stc.For veterinary use only. Keep out of the reach of chlidren. the package generally bottled Then pretend to box packing,then loading in the carton.

Animal Antibacterial Drugs

Animal Antibiotics,Chicken Antibiotics,Cattle Antibiotics,Livestock Antibiotics

Hebei Kexing Pharmaceutical Co., Ltd. , http://www.kexingpharma.com

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