CAS: 58-93-5Â
MF: C7H8ClN3O4S2Â
MW: 297.74Â
EINECS: 200-403-3Â
Chemical Properties It is a kind of white crystalline powder with the melting point being 273-275 ºC. It is soluble in acetone, slightly soluble in alcohol, insoluble in water, chloroform, ether, and soluble in sodium hydroxide solution but being susceptible to hydrolysis. It has a slightly bitter taste. Â
Uses The product is a typical representative in the thiazide diuretic drug with its pharmaceutical sales in United States ranking first in 1985. Owing to its easy administration, moderate action as well as being suitable for all kinds of edema, it is most often clinically applied. Owing to adverse reactions like potassium secretion, we should pay attention to supplement potassium salt during the application. Intravenous injection-mice-LD50: 590mg / kg, oral LD50: greater than 8000mg / kg.Â
DiureticsÂ
It mainly inhibits the re-absorption on Na+ and Cl- by the proximal end of the distal convoluted tubule so that renal excretion of sodium chloride is increased to produce a diuretic effect. It is a kind of diuretic drugs of moderate effect. This product has antihypertensive effect with the effect being enhanced when being use in combination with Lee medicine paste, antihypertensive shen paste or apocynum venetum and other traditional Chinese medicine. This product also has anti-diuretic effect and can be used for the treatment of diabetes insipidus Â
Production method It is produced by: m-Chlorosulfonated goes through chlorosulfonation to give 5-chloro-2,4-chloro-anilide, and further reacted with ammonia to form 5-chloro-2,4-sulfamoyl aniline which finally reacts with formaldehyde to obtain the final product. Â
Chemical Properties White SolidÂ
Category toxic substances Â
Usage A carbonic anhydrase inhibitor. Diuretic.Â
Usage Labelled Hydrochlorothiazide (H714560). Hydrochlorothiazide is a carbonic anhydrase inhibitor as a diuretic.Â
Our Adwantage:
1.We have stock so we can delivery quickly at the very day when receive the payment.
2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.
3.High quality guarenteed, once any problem is found, the package would be reshipped for you
4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air.The most professional forwarder would be recommanded for you.
5. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.Adhering to the principle of customer first conviction.we will provide the best and the most sincere services as possible as we can.
FAQ
1.What services do you offer?
We can offer the Custom premixes, Semi-Finished products, Finished products, OEM service.
We can also assist with formulations, blends and custom packing. QHNUTRACEUTICALS is your complete source for today and tomorrow's most potent and popular natural ingredients. With experience of more than 500 formula products, if you can envision a functional product, we can make it happen.
2.How do I make an order?
Simply contact our office by telephone +86-027-81302011 .We will connect you with one of our account managers who will be happy to assist you with your order.
Synonyms: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide;2h-1,2,4-benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-,1,1-dioxide;3,4-Dihydro-6-chloro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide;6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide;6-Chloro-3,4-dihydro-7-sulphamoyl-1,2,4-ben-zoth-iadi-azine1,1-dioxcide;6-chloro-7-sulfamoyl-3,4-dihydro-2h-1,2,4-benzothiadiazine;6-Chloro-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide;6-chloro-7-sulfamoyl-3,4-dihydro-2h-1,2,4-benzothiadiazine-1,1-dioxideÂ
CAS: 58-93-5Â
MF: C7H8ClN3O4S2Â
MW: 297.74Â
EINECS: 200-403-3Â
Chemical Properties It is a kind of white crystalline powder with the melting point being 273-275 ºC. It is soluble in acetone, slightly soluble in alcohol, insoluble in water, chloroform, ether, and soluble in sodium hydroxide solution but being susceptible to hydrolysis. It has a slightly bitter taste. Â
Uses The product is a typical representative in the thiazide diuretic drug with its pharmaceutical sales in United States ranking first in 1985. Owing to its easy administration, moderate action as well as being suitable for all kinds of edema, it is most often clinically applied. Owing to adverse reactions like potassium secretion, we should pay attention to supplement potassium salt during the application. Intravenous injection-mice-LD50: 590mg / kg, oral LD50: greater than 8000mg / kg.Â
DiureticsÂ
It mainly inhibits the re-absorption on Na+ and Cl- by the proximal end of the distal convoluted tubule so that renal excretion of sodium chloride is increased to produce a diuretic effect. It is a kind of diuretic drugs of moderate effect. This product has antihypertensive effect with the effect being enhanced when being use in combination with Lee medicine paste, antihypertensive shen paste or apocynum venetum and other traditional Chinese medicine. This product also has anti-diuretic effect and can be used for the treatment of diabetes insipidus Â
Production method It is produced by: m-Chlorosulfonated goes through chlorosulfonation to give 5-chloro-2,4-chloro-anilide, and further reacted with ammonia to form 5-chloro-2,4-sulfamoyl aniline which finally reacts with formaldehyde to obtain the final product. Â
Chemical Properties White SolidÂ
Category toxic substances Â
Usage A carbonic anhydrase inhibitor. Diuretic.Â
Usage Labelled Hydrochlorothiazide (H714560). Hydrochlorothiazide is a carbonic anhydrase inhibitor as a diuretic.Â
Our Adwantage:
1.We have stock so we can delivery quickly at the very day when receive the payment.
2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.
3.High quality guarenteed, once any problem is found, the package would be reshipped for you
4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air.The most professional forwarder would be recommanded for you.
5. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.Adhering to the principle of customer first conviction.we will provide the best and the most sincere services as possible as we can.
FAQ
1.What services do you offer?
We can offer the Custom premixes, Semi-Finished products, Finished products, OEM service.
We can also assist with formulations, blends and custom packing. QHNUTRACEUTICALS is your complete source for today and tomorrow's most potent and popular natural ingredients. With experience of more than 500 formula products, if you can envision a functional product, we can make it happen.
2.How do I make an order?
Simply contact our office by telephone +86-027-81302011 .We will connect you with one of our account managers who will be happy to assist you with your order.
High Purity and High Quality; CAS: 58-93-5
Model NO.: 58-93-5
Color: White
Delivery: by DHL, TNT, FedEx, Hkems, UPS, etc
Trademark: dky
Specification: USP/BP/EP/CP
Origin: China
Model NO.: 58-93-5
Color: White
Delivery: by DHL, TNT, FedEx, Hkems, UPS, etc
Trademark: dky
Specification: USP/BP/EP/CP
Origin: China
Synonyms: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide;2h-1,2,4-benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-,1,1-dioxide;3,4-Dihydro-6-chloro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide;6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide;6-Chloro-3,4-dihydro-7-sulphamoyl-1,2,4-ben-zoth-iadi-azine1,1-dioxcide;6-chloro-7-sulfamoyl-3,4-dihydro-2h-1,2,4-benzothiadiazine;6-Chloro-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide;6-chloro-7-sulfamoyl-3,4-dihydro-2h-1,2,4-benzothiadiazine-1,1-dioxideÂ