The first new therapeutic gene vaccine for the treatment of type 1 diabetes was born

Release date: 2016-11-08

Recently, the reporter learned from the 307 Hospital that the team led by the researcher of the Institute of Immunology and the famous blood immunologist, Yong Yongzhi, has been working for more than 20 years and successfully developed the first co-stimulation pathway based on B7-CD28/CTLA4 in the world. A new therapeutic gene vaccine for the treatment of type 1 diabetes. This is the latest breakthrough in the field of type I diabetes biotherapy in China. It is an original achievement with China's completely independent intellectual property rights. It has successively obtained “three-party” patents from China, the United States and the European Union. At the same time, the Japanese invention patent applied for is in the process of replying to the review. The “three-party patent” is one of the standards recognized by the international community to evaluate whether a country has reached an innovative country, and it can more truly reflect the quality and competitiveness of technology and output.

It is reported that China is the country with the largest number of diabetes patients in the world, with a total of 110 million, of which type I diabetes (T1DM), also known as insulin-dependent diabetes, totals nearly 10 million. T1DM is a kind of metabolic disease, which belongs to the category of autoimmune diseases. Its pathological features are abnormal autoimmune cellular and humoral immune responses, leading to the reduction of islet β cell damage and insulin secretion, which seriously endangers human health. The effective treatment of T1DM is still a long-term supplement for insulin or insulin analogues. From the previous research data, the therapeutic gene vaccine developed by Yan Yongzhi's team can reduce the long-term dependence of patients on insulin, reduce the side effects caused by long-term injection of insulin, significantly reduce medical costs, and significantly reduce the frequency of treatment. At present, the team is actively promoting the application of the genetic vaccine patent to transform the society as soon as possible.

Source: Science Network

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What is DVR Mini Camera

Dvr, which is called DigitalVideoRecorder in full, is a digital video recorder. Compared with traditional analog video recorders, dvr uses hard disk for recording, so it is often called hard disk recorder, also called DVR. It is a set of computer system for image computing, storage and processing. It has the functions of long-time video recording, recording, remote monitoring and control of images/voice and dynamic frames. DVR integrates five functions, including video recorder, picture splitter, PTZ lens control, alarm control, and network transmission. One device can replace a large number of devices in the analog monitoring system, Moreover, it has gradually gained advantages and popularity in terms of price.

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DVRs cannot support IP cameras. From a general definition, products called DVRs generally do not support IP network cameras. Digital DVRs generally refer to converting video data captured by analog cameras into digital recordings, and do not include IP network transmission. By definition, DVR intelligence supports the input of analog signals. Therefore, if the DVR supports IP cameras, it is necessary to decode the IP cameras into analog signal signals using a decoder in the front section before entering the DVR.
The "digitalization" of DVR means that compression and storage technology is aimed at digital signals, rather than directly transmitting digitally encoded video images. Therefore, DVR must be deployed near the analog camera.

The function of DVR, with the increase of various voltage sensitive loads in the distribution network, puts forward higher requirements for power quality. However, due to system accidents in the power system, the voltage flicker, drop and other disturbances caused by the startup and shutdown of large equipment, lightning stroke and other principles are unavoidable. Moreover, in the current power grid, the ability to quickly restore power supply after power interruption is far from meeting the requirements of many sensitive loads. Therefore, it is necessary to provide users with stable and uninterrupted high-quality power when interference occurs. Dynamic voltage recovery (DVR) is the choice to solve the above problems today. DVR is connected in series to the feeder line that requires high-quality power to realize dynamic real-time voltage compensation for the line, so that the load end can get the desired high-quality power, and ensure the normal and uninterrupted operation of sensitive user equipment.

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